Context. The identification of the sources that reionized the Universe and their specific contribution to this process are key missing pieces of our knowledge of the early Universe. Faint star-forming galaxies may be the main contributors to the ionizing photon budget during the epoch of reionization, but their escaping photons cannot be detected directly due to inter-galactic medium opacity. Hence, it is essential to characterize the properties of faint galaxies with significant Lyman continuum photon leakage up to z 4 to (...) define indirect indicators allowing analogues to be found at the highest redshift. Aims. Long gamma-ray bursts explode typically in star-forming regions of faint, star-forming galaxies. Through LGRB afterglow spectroscopy it is possible to detect directly LyC photons. Our aim is to use LGRBs as tools to study LyC leakage from faint, star-forming galaxies at high redshift. Methods. Here we present the observations of LyC emission in the afterglow spectra of GRB 191004B at z = 3:5055, together with those of the other two previously known LyC-emitting LGRB, to determine their LyC escape fraction and compare their properties. Results. From the afterglow spectrum of GRB 191004B we determine a neutral hydrogen column density at the LGRB redshift of og =17:2 0:15, and negligible extinction. The only metal absorption lines detected are C iv and Si iv. In contrast to GRB 050908 and GRB 060607A, the host galaxy of GRB 191004B displays significant Ly emission. From its Ly emission and the non-detection of Balmer emission lines we constrain its star-formation rate to 1 SFR 4:7 M yr. 1. We fit the Ly emission with a shell model and find parameters values consistent with the observed ones. The absolute LyC escape fractions we find for GRB 191004B, GRB 050908 and GRB 060607A are of 0:35+0:10.0:11, 0:08+0:05.0:04 and :20+0:05.0:05, respectively. We compare the LyC escape fraction of LGRBs to the values of other LyC emitters found from the literature, showing that LGRB afterglows can be powerful tools to study LyC escape for faint high-redshift star-forming galaxies. Indeed we could push LyC leakage studies to much higher absolute magnitudes. The host galaxies of the three LGRB presented here have all M1600 >.19:5 mag, with the GRB 060607A host at M1600 >.16 mag. LGRB hosts may therefore be particularly suitable for exploring the ionizing escape fraction in galaxies that are too faint or distant for conventional techniques. Furthermore the time investment is very small compared to galaxy studies. (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

Lives on the Fringes: Interdisciplinary Approaches to Incarceration Editors: Caterina Benelli, Giovanni Cogliandro, Giovanna Costanzo.

The fundamental tenet of contemporary sociobiology, namely the assumption of a single process of evolution involving the selection of genes, is critically examined. An alternative multiple-level, multiple-process model of evolution is presented which posits that the primary process that operates via selection upon the genes cannot account for certain kinds of biological phenomena, especially complex, learned, social behaviours. The primary process has evolved subsidiary evolutionary levels and processes that act to bridge the gap between genes and these complex behaviours. The (...) subsidiary levels are development, individual animal learning, and socioculture itself. It is argued that individual learning is pivotal to the derivation and biological analysis of culture. The differences between cultural and noncultural societies are stressed. It is concluded that such a multiple-level model of evolution can form the basis for reconciling opposing sides in the sociobiology debate. (shrink)

Branner, H.C. Humanismens krise.--Hansen, Martin A. Eneren og massen.

In a note on this passage as far back as 1868, E. Wölmin 1 advanced the theory that the plural anulis is used here in a technical and stereotyped way as symbolic of equestrian rank. He is not sure whether such illogical use of the plural is to be found earlier than Tacitus or not.

In describing the account of the εδη in the Phaedo, Burnet says, ‘they are explained in a peculiar vocabulary which is represented as that of a school. The technical terms are introduced by such formulas as “we say”’. Similarly Taylor has written of the ‘characteristic technical nomenclature’ used in the dialogues, of the ‘technicalities’ of the theory of εδη, of ‘the technical phrases of the Phaedo’ The validity of such language has been taken for granted by both these and many (...) other Platonic scholars. But the assumption which it represents—that Plato employed certain words in a significance peculiar to his use of them—carries such wide implications for the history and interpretation of his philosophy that it can hardly be accepted without further investigation. In this article I shall examine the evidence in fifth- and early fourth-century literature about these words which Plato or Socrates is alleged to have transformed into ‘technicalities’: first, εδος and δσ, which I shall assume to be more or less synonymous; second, the various terms used to describe the relation between εδη and particulars—,μετέχειν, κοινωνεν,παρεναι, νεναι,μιμησις,μοιωαις, and so on. (shrink)

‘Vergil lässt keinen Zweifel darüber, dass in Wahrheit das Fatum nichts anderes ist als des höchsten Gottes Wille.’ Thus Heinze, apparently following an observation by Seruius auctus, and in turn generally followed by scholars who have subsequently considered the nature of the fata in the Aeneid. But questions concerning the interpretation of the Aeneid are rarely simple; and the question of Jupiter's relationship to the fata may repay further enquiry.

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